Your post made me chuckle, I feel like a mad scientist at times also!
If you worry about using up your oils on potential mix disasters then try the q-tip test. This saved me so much money because I only had to wet the q-tips instead of using up larger volumes of expensive oils in blends that didn't work out. Tell your wife if she has an idea for a blend to dip a q-tip in each of the oils in the projected blend, I don't know what proportions she blended the oils for the German Chocolate Cake, let's say it was 1:1:1:1 of the four oils. Use one q-tip for each of the four oils and put them in a jar with the lid on. Open the jar later after the fo's have had a chance to blend, if the mix isn't right to your nose then add an extra q-tip dipped in the scent that doesn't seem strong enough. For example, if you can't smell the coconut add another q-tip of coconut. Now your blend is 2:1:1:1. Keep adding q-tips with oils until it smells the way you want it to and then blend the oils in those proportions in a larger bottle.
My most complicated experiment was trying to duplicate a Starbucks holiday drink, I think it was a pumpkin vanilla latte or something similar, the coffee over powered everything else so it took many additions of pumpkin, vanilla, etc. until I had it right.
Good luck blending, it's a lot of fun!